NHEJ1 polyclonal antibody
产品名称： NHEJ1 polyclonal antibody
英文名称： NHEJ1 polyclonal antibody
产品编号： PAB7119
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Goat polyclonal antibody raised against synthetic peptide of NHEJ1.
- Immunogen:
- A synthetic peptide corresponding to C terminus of human NHEJ1.
- Sequence:
- C-QRPQLSKVKRKKPR
- Host:
- Goat
- Theoretical MW (kDa):
- 33.3
- Reactivity:
- Human
- Form:
- Liquid
- Purification:
- Antigen affinity purification
- Concentration:
- 0.5 mg/mL
- Storage Buffer:
- In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)
- Storage Instruction:
- Store at -20°C.
Aliquot to avoid repeated freezing and thawing.
- Recommend Usage:
- ELISA (1:64000)
Western Blot (0.1-0.3 ug/mL)
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (2.5-3.8 ug/mL)
The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Publication Reference
- 1.
- XLF interacts with the XRCC4-DNA ligase IV complex to promote DNA nonhomologous end-joining.
Ahnesorg P, Smith P, Jackson SP.Cell. 2006 Jan 27;124(2):301-13.
- Applications
- Western Blot (Tissue lysate)
- NHEJ1 polyclonal antibody (Cat # PAB7119) (0.1 ug/mL) staining of human thyroid lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
- Entrez GeneID:
- 79840
- Protein Accession#:
- NP_079058.1
- Gene Name:
- NHEJ1
- Gene Alias:
- FLJ12610,XLF
- Gene Description:
- nonhomologous end-joining factor 1
- Omim ID:
- 611290
- Gene Ontology:
- Hyperlink
- Gene Summary:
- Double-strand breaks in DNA result from genotoxic stresses and are among the most damaging of DNA lesions. This gene encodes a DNA repair factor essential for the nonhomologous end-joining pathway, which preferentially mediates repair of double-stranded breaks. Mutations in this gene cause different kinds of severe combined immunodeficiency disorders. [provided by RefSeq
- Other Designations:
- Cernunnos,XRCC4-like factor
- Gene Pathway