PLAT (Human) Recombinant Protein
产品名称: PLAT (Human) Recombinant Protein
英文名称: PLAT (Human) Recombinant Protein
产品编号: P3670
产品价格: 0
产品产地: 台湾
品牌商标: Abnova
更新时间: null
使用范围: null
                            亚诺法生技股份有限公司(Abnova)
                            
                                
                            
                        
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 - 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
 - 邮编 : 11493
 - 所在区域 : 台湾
 - 电话 : +886-920**1152 点击查看
 - 传真 : 点击查看
 - 邮箱 : sales@abnova.com.tw
 
- Specification
 
- Product Description:
 - Human PLAT (P00750, 36 a.a. - 562 a.a.) partial recombinant protein expressed in CHO cells.
 
- Sequence:
 - SYQVICRDEKTQMIYQQHQSWLRPVLRSNRVEYCWCNSGRAQCHSVPVKSCSEPRCFNGGTCQQALYFSDFVCQCPEGFAGKCCEIDTRATCYEDQGISYRGTWSTAESGAECTNWNSSALAQKPYSGRRPDAIRLGLGNHNYCRNPDRDSKPWCYVFKAGKYSSEFCSTPACSEGNSDCYFGNGSAYRGTHSLTESGASCLPWNSMILIGKVYTAQNPSAQALGLGKHNYCRNPDGDAKPWCHVLKNRRLTWEYCDVPSCSTCGLRQYSQPQFRIKGGLFADIASHPWQAAIFAKHRRSPGERFLCGGILISSCWILSAAHCFQERFPPHHLTVILGRTYRVVPGEEEQKFEVEKYIVHKEFDDDTYDNDIALLQLKSDSSRCAQESSVVRTVCLPPADLQLPDWTECELSGYGKHEALSPFYSERLKEAHVRLYPSSRCTSQHLLNRTVTDNMLCAGDTRSGGPQANLHDACQGDSGGPLVCLNDGRMTLVGIISWGLGCGQKDVPGVYTKVTNYLDWIRDNMRP
 
- Theoretical MW (kDa):
 - 60
 
- Form:
 - Lyophilized
 
- Preparation Method:
 - Mammalian cell (CHO) expression system
 
- Purification:
 - Ion exchange column and HPLC reverse phase column
 
- Purity:
 - > 98% by SDS-PAGE and HPLC
 
- Endotoxin Level:
 - < 0.1 ng/ug (1 EU/ug)
 
- Activity:
 - The activity was determined to be 6 x 105 IU/mg.
 
- Storage Buffer:
 - Lyophilized from 0.2 M L-arginine, 0.1 M phosphoric acid
 
- Storage Instruction:
 - Store at -20°C on dry atmosphere for 2 years.
After reconstitution with deionized water, store at 4°C for 1 month or store at -20°C for 6 months.
Aliquot to avoid repeated freezing and thawing. 
- Application Image
 
- Functional Study
 
- SDS-PAGE
 
- Entrez GeneID:
 - 5327
 
- Protein Accession#:
 - P00750
 
- Gene Name:
 - PLAT
 
- Gene Alias:
 - DKFZp686I03148,T-PA,TPA
 
- Gene Description:
 - plasminogen activator, tissue
 
- Omim ID:
 - 173370
 
- Gene Ontology:
 - Hyperlink
 
- Gene Summary:
 - This gene encodes tissue-type plasminogen activator, a secreted serine protease which converts the proenzyme plasminogen to plasmin, a fibrinolytic enzyme. Tissue-type plasminogen activator is synthesized as a single chain which is cleaved by plasmin to a two chain disulfide linked protein. This enzyme plays a role in cell migration and tissue remodeling. Increased enzymatic activity causes hyperfibrinolysis, which manifests as excessive bleeding; decreased activity leads to hypofibrinolysis which can result in thrombosis or embolism. Alternative splicing of this gene results in multiple transcript variants encoding different isoforms. [provided by RefSeq
 
- Other Designations:
 - alteplase,plasminogen activator, tissue type,reteplase,t-plasminogen activator,tissue plasminogen activator (t-PA)
 
- Gene Pathway
 
- Related Disease
 
- Alzheimer Disease
 - Alzheimer disease
 - Amphetamine-Related Disorders
 - Aneurysm, Ruptured
 - Arterial Occlusive Diseases
 - Arteriosclerosis
 - Arthritis, Rheumatoid
 - Atherosclerosis
 - Atherosclerosis
 - Brain Infarction
 - Brain Ischemia
 - Calcinosis
 - Cardiovascular Diseases
 - Cerebral Palsy
 - Cerebrovascular Accident
 - Chorioamnionitis
 - Connective Tissue Diseases
 - Coronary Artery Disease
 - Coronary Disease
 
