AURKC (isoform 3) (Human) Recombinant Protein
产品名称： AURKC (isoform 3) (Human) Recombinant Protein
英文名称： AURKC (isoform 3) (Human) Recombinant Protein
产品编号： P5686
产品价格： 0
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围： null
亚诺法生技股份有限公司（Abnova)
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- Specification
- Product Description:
- Human AURKC (NP_002392.2, 1 a.a. - 275 a.a.) full-length recombinant protein with GST tag expressed in Baculovirus infected Sf21 cells.
- Theoretical MW (kDa):
- 59
- Form:
- Liquid
- Preparation Method:
- Baculovirus expression system
- Purification:
- Glutathione sepharose chromatography
- Purity:
- 80 % by SDS-PAGE/CBB staining
- Activity:
- The activity was measured by off-chip mobility shift assay. The enzyme was incubated with fluorecence-labeled substrate and Mg (or Mn)/ATP. The phosphorylated and unphosphorylated substrates were separated and detected by LabChip™3000.
Substrate : Kemptide. ATP: 100 µM.
- Storage Buffer:
- In 50 mM Tris-HCl, 150 mM NaCl, pH 7.5 (0.1% CHAPS, 1 mM DTT, 10% glycerol)
- Storage Instruction:
- Store at -80°C.
Aliquot to avoid repeated freezing and thawing.
- Quality Control Testing:
- Loading 1 ug protein in SDS-PAGE
- Note:
- Result of activity analysis
-
- Application Image
- Functional Study
- SDS-PAGE
- Entrez GeneID:
- 6795
- Protein Accession#:
- NP_003151.2
- Gene Name:
- AURKC
- Gene Alias:
- AIE2,AIK3,AurC,STK13,aurora-C
- Gene Description:
- aurora kinase C
- Gene Ontology:
- Hyperlink
- Gene Summary:
- This gene encodes a member of the Aurora subfamily of serine/threonine protein kinases. The encoded protein is a chromosomal passenger protein that forms complexes with Aurora-B and inner centromere proteins and may play a role in organizing microtubules in relation to centrosome/spindle function during mitosis. This gene is overexpressed in several cancer cell lines, suggesting an involvement in oncogenic signal transduction. Alternative splicing results in multiple transcript variants. [provided by RefSeq
- Other Designations:
- aurora/IPL1-related kinase 3,aurora/IPL1/EG2 protein 2,serine/threonine kinase 13 (aurora/IPL1-like)
- Related Disease