白介素-5受体α链抗体IL-5Rα
产品名称: 白介素-5受体α链抗体IL-5Rα
英文名称: IL5RA
产品编号: bs-2601R
产品价格: null
产品产地: 北京
品牌商标: BIOSS
更新时间: 2025-12-25T09:40:42
使用范围: WB=1:100-500,ELISA=1:500-1000,IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500,
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The protein encoded by this gene is an interleukin 5 specific subunit of a heterodimeric cytokine receptor. The receptor is comprised of a ligand specific alpha subunit and a signal transducing beta subunit shared by the receptors for interleukin 3(IL3), colony stimulating factor 2 (CSF2/GM-CSF), and interleukin 5(IL5). The binding of this protein to IL5 depends on the beta subunit. The beta subunit is activated by the ligand binding, and is required for the biological activities of IL5. This protein has been found to interact with syndecan binding protein (syntenin), which is required for IL5 mediated activation of the transcription factor SOX4. Six alternatively spliced transcript variants encoding three distinct isoforms have been reported.
